TK4b
TK4b is a potent Janus kinase (JAK) inhibitor, demonstrating high selectivity for JAK3 (IC50 = 18.42 nM) and JAK2 (IC50 = 19.40 nM) . This small molecule is a valuable research tool for investigating JAK-STAT signaling pathways in the context of leukemia and lymphoid disorder research, both in vitro and in vivo.
Product Specifications
CAS Number
2232890-81-0
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (C) N1N (C (=O) C (C (=O) C2=CC=CC=C2) =C1C) C3=CC (C) =C (C) C=C3
Molecular Formula
C21H22N2O2
Molecular Weight
334.41
Storage Conditions
-20°C
Notes
For research use only.
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