GSK-1482160
GSK-1482160 is an orally active, brain-penetrant negative allosteric modulator of the pro-inflammatory P2X7 receptor. It exhibits potent and selective in vitro activity across species, supporting its use in research models of neuroinflammation, chronic pain, and autoimmune disorders.
Product Specifications
CAS Number
1001389-72-5
Product Name Alternative
P2X7, P2XReceptor, P2X Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.57% (May vary between batches)
Solubility
DMSO:90 mg/mL (268.88 mM)
Smiles
CN1[C@@H] (CCC1=O) C (=O) NCc1cccc (c1Cl) C (F) (F) F
Molecular Formula
C14H14ClF3N2O2
Molecular Weight
334.72
Storage Conditions
-20°C
Notes
For research use only.
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