Carbonic anhydrase inhibitor 10

This small molecule carbonic anhydrase inhibitor exhibits potent anti-proliferative activity against MCF-7 breast cancer cells (IC50 = 11.9 μM) and is a strong, selective inhibitor of the tumor-associated isoform hCA IX (Ki = 6.2 nM) . It is a valuable research tool for studying hypoxia and acidosis in cancer biology, applicable in both in vitro and in vivo experimental models.