ANO1-IN-1
ANO1-IN-1 is a selective small-molecule inhibitor of ANO1 (TMEM16A) with an IC50 of 2.56 μM, showing lower potency against ANO2 (IC50 = 15.43 μM) . This compound has been shown to suppress glioma cell proliferation in vitro, making it a useful research tool for studying calcium-activated chloride channels in cancer and other physiological contexts.
Product Specifications
CAS Number
407587-01-3
Product Name Alternative
ANO1, ANO2, Chloridechannel, Chloride channel
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.66% (May vary between batches)
Solubility
10% DMSO+90% Saline:5 mg/mL (14.86 mM) ; DMSO:150 mg/mL (445.78 mM)
Smiles
C (N) (=O) C=1C2=C (SC1NC (C (C) (C) C) =O) CC (C (C) (C) C) CC2
Molecular Formula
C18H28N2O2S
Molecular Weight
336.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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