SCH-42354
SCH-42354 is a potent, orally active neutral endopeptidase (NEP) inhibitor, derived from the prodrug SCH-42495. It enhances atrial natriuretic peptide (ANP) activity and inhibits the hydrolysis of leu-enkephalin and ANF with low nanomolar IC50 values. This compound demonstrates antihypertensive effects and is a valuable research tool for cardiovascular and neuropeptide studies in vitro and in vivo.
Product Specifications
CAS Number
144505-58-8
Field of Research
Metabolism Research, Signal Transduction
Smiles
C ([C@@H] (C (N[C@@H] (CCSC) C (O) =O) =O) CS) C1=C (C) C=CC=C1
Molecular Formula
C16H23NO3S2
Molecular Weight
341.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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