UCB-5307
UCB-5307 is a small molecule inhibitor of TNFR1 signaling that binds human TNFα with high affinity (K_D ~6-9 nM) via slow kinetics and can disrupt pre-formed TNF/TNFR1 complexes. Its utility in exploring TNF-driven pathology makes it a valuable tool for in vitro and in vivo inflammatory disease research.
Product Specifications
CAS Number
1515887-44-1
Product Name Alternative
TNF-α
Field of Research
Cell Biology
Purity
98.02% (May vary between batches)
Solubility
DMSO:65 mg/mL (189.27 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.82 mM)
Smiles
Cc1ccc (C) c (Cn2c (nc3ccccc23) C (O) c2ccncc2) c1
Molecular Formula
C22H21N3O
Molecular Weight
343.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
