c-erbB2 (HER-2, neu Receptor)
Product Specifications
Reactivity
Human
Storage Conditions
May be stored at 4 °C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at-20 °C or colder. Aliquots are stable for at least 12 months at-20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Specificity
Reacts with the intact cells,1,2 slightly increases (~2-fold) the tyrosine kinase activity,1 accelerates (~50%) c-erbB-2 turnover,1 and inhibits (~80%) tumorigenic growth in CD1/nude mice of N87 human gastric carcinoma cell line overexpressing c-erbB-2.1 Species Crossreactivity: human. Does not react with mouse and rat.
Short Name
[c-erbB2]
Other Product Names
[Chain P, Single Chain Fv Of C219 Heavy Chain V101l Mutant In Complex With Synthetic Epitope Peptide]
NCBI GI Number
37926854
Available Sizes
Curated Selection
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