JG-23
JG-23 is a 4-chloro modified analog with ability to promote t-tau degradation. JG-23 exhibits good metabolic stability with a long T1/2 value (36 min) in mouse liver microsome assays[1].
Product Specifications
UNSPSC
12352005
Target
Tau Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jg-23.html
Purity
99.64
Solubility
DMSO : 4.55 mg/mL (ultrasonic; warming; heat to 160°C)
Smiles
CN1/C(SC2=CC=C(Cl)C=C21)=C3C(N(/C(S/3)=C/C4=CC=NC=C4)CC)=O
Molecular Formula
C19H16ClN3OS2
Molecular Weight
401.93
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153822/JG-23-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153822/JG-23-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[2640819-75-4]
Available Sizes
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