CA224
CA224 (Compound 1) is an orally bioavailable, selective inhibitor of the Cdk4/cyclin D1 complex with an IC50 of 6.2 μM. This small molecule induces apoptosis and demonstrates antitumor activity, supporting its use in cancer research for both in vitro mechanistic studies and in vivo efficacy models.
Product Specifications
CAS Number
883561-04-4
Field of Research
Cell Biology
Smiles
C (CN (C (=O) C1=CC=C (C=C1) C2=CC=CC=C2) C) C=3C=4C (NC3) =CC=CC4
Molecular Formula
C24H22N2O
Molecular Weight
354.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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