SRI-41315
SRI-41315 is a molecular glue degrader of eRF1 that induces ribosomal pausing at premature termination codons (PTCs) . It has been shown to restore CFTR function in both immortalized and primary human bronchial epithelial cells, demonstrating its potential for research in cystic fibrosis and nonsense mutation-mediated diseases.
Product Specifications
CAS Number
1613509-49-1
Product Name Alternative
SRI41315
Field of Research
Pharmacology & Drug Discovery
Purity
99.87% (May vary between batches)
Solubility
DMSO:16 mg/mL (44.77 mM)
Smiles
O=C1C=2C=CC=CC2N (C=3N=C (N (C=4C=CC=CC4) C (=O) C13) C5CCC5) C
Molecular Formula
C22H19N3O2
Molecular Weight
357.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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