PARP1-IN-9
PARP1-IN-9 (Compound 5c) is a potent PARP1 inhibitor with an IC50 of 30.51 nM, demonstrating superior efficacy to Olaparib in vitro. It induces apoptosis and exhibits anticancer activity, making it a valuable tool for oncology research, including studies of DNA damage response and synthetic lethality in cellular models.
Product Specifications
CAS Number
2494000-71-2
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
C (C1=CC (C=C2C (=O) NC (=O) NC2=O) =CC (OC) =C1O) N3CCCCC3
Molecular Formula
C18H21N3O5
Molecular Weight
359.38
Storage Conditions
-20°C
Notes
For research use only.
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