Rucaparib hydrochloride
Rucaparib hydrochloride (AG014699) is a potent, orally active PARP-1/2/3 inhibitor (Ki=1.4 nM for PARP1) and a modest H6PD inhibitor. It is a research tool for studying DNA damage response and has demonstrated activity in preclinical models of castration-resistant prostate cancer and other BRCA-deficient cancers.
Product Specifications
CAS Number
773059-19-1
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Smiles
Cl.CNCc1ccc (cc1) -c1[nH]c2cc (F) cc3C (=O) NCCc1c23
Molecular Formula
C19H19ClFN3O
Molecular Weight
359.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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