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Rucaparib hydrochloride

Rucaparib hydrochloride (AG014699) is a potent, orally active PARP-1/2/3 inhibitor (Ki=1.4 nM for PARP1) and a modest H6PD inhibitor. It is a research tool for studying DNA damage response and has demonstrated activity in preclinical models of castration-resistant prostate cancer and other BRCA-deficient cancers.

Product Specifications

CAS Number

773059-19-1

Field of Research

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Smiles

Cl.CNCc1ccc (cc1) -c1[nH]c2cc (F) cc3C (=O) NCCc1c23

Molecular Formula

C19H19ClFN3O

Molecular Weight

359.83

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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