IEM 1754 2HBr
IEM 1754 dihydrobromide is a selective antagonist of AMPA/kainate receptors, specifically targeting GluR1 and GluR3 subunits with an IC50 of 6 μM. This compound is a valuable research tool for investigating excitatory neurotransmission in neurological studies, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
162831-31-4
Product Name Alternative
Inhibit, Ionotropic glutamate receptors, NMDA receptor, mGluR3, mGluR1, iGluR, IEM 1754, IEM 1754 2HBr, IEM 1754 dihydrobromide, IEM 1754 Dihydrobromide, IEM1754, IEM-1754, IEM1754 Dihydrobromide, IEM-1754 Dihydrobromide, Inhibitor, channel block, AMPA receptor, voltage dependence
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.43 mM) ; DMSO:50 mg/mL (121.29 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:75 mg/mL (181.93 mM)
Smiles
Br.Br.NCCCCCNCC12CC3CC (CC (C3) C1) C2
Molecular Formula
C16H30N2·2HBr
Molecular Weight
412.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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