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VO-OHPic

VO-OHPic is a potent, selective, and reversible noncompetitive PTEN inhibitor (IC50 = 46 nM) . It has demonstrated protective effects in doxorubicin-induced cardiomyopathy models by reducing apoptosis, cardiac remodeling, and M1 macrophage polarization, while also inhibiting autophagy.

Product Specifications

CAS Number

675848-25-6

Field of Research

Cell Biology, Signal Transduction

Smiles

[O-][V]=O.OC (=O) c1ncccc1O.OC (=O) c1ncccc1O

Molecular Formula

C12H10N2O8V

Molecular Weight

361.16

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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