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ARN25068

ARN25068 is a sub-micromolar inhibitor of GSK-3β, FYN, and DYRK1A kinases. It reduces pathological tau hyperphosphorylation, making it a useful research tool for studying neurodegenerative mechanisms in cellular and animal models of tauopathy.

Product Specifications

CAS Number

2649882-80-2

Product Name Alternative

MicrotubuleAssociated, Microtubule Associated, Fyn, GSK-3β, GSK3, DYRK1A, tau

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.71% (May vary between batches)

Solubility

DMSO:55 mg/mL (151.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.8 mM)

Smiles

N (C1=C2C (=NC (NCC3=CC=CC=C3) =N1) C=CS2) C=4C=C (NN4) C5CC5

Molecular Formula

C19H18N6S

Molecular Weight

362.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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