ARN25068
ARN25068 is a sub-micromolar inhibitor of GSK-3β, FYN, and DYRK1A kinases. It reduces pathological tau hyperphosphorylation, making it a useful research tool for studying neurodegenerative mechanisms in cellular and animal models of tauopathy.
Product Specifications
CAS Number
2649882-80-2
Product Name Alternative
MicrotubuleAssociated, Microtubule Associated, Fyn, GSK-3β, GSK3, DYRK1A, tau
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.71% (May vary between batches)
Solubility
DMSO:55 mg/mL (151.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.8 mM)
Smiles
N (C1=C2C (=NC (NCC3=CC=CC=C3) =N1) C=CS2) C=4C=C (NN4) C5CC5
Molecular Formula
C19H18N6S
Molecular Weight
362.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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