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Bromodomain inhibitor-10

Bromodomain inhibitor-10 (compound 128) is a potent, dual-bromodomain inhibitor with high affinity for BRD4-1 (Kd=15 nM) and BRD4-2 (Kd=2500 nM) . It suppresses IL12p40 production and is a valuable chemical probe for epigenetic and inflammation research in cellular and biochemical assays.

Product Specifications

CAS Number

1870849-58-3

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Smiles

C (NC=1C=C2C (=CC1) NC (=O) C=C2C) (=O) C3=C (N=CC=C3) N4CCOCC4

Molecular Formula

C20H20N4O3

Molecular Weight

364.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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