Gü1303
Gü1303 is a potent, reversible Cathepsin K (CatK) inhibitor with a Ki of 0.91 nM against the mature enzyme. It also inhibits the autocatalytic activation of the CatK zymogen. This compound is a valuable research tool for studying bone resorption, osteoporosis, and arthritis in both cellular and animal models.
Product Specifications
CAS Number
1043922-53-7
Field of Research
Protein Biochemistry
Smiles
[C@H] (CC1=CC=CC=C1) (C (N (N (C#N) C) C) =O) NC (OCC2=CC=CC=C2) =O
Molecular Formula
C20H22N4O3
Molecular Weight
366.41
Storage Conditions
-20°C
Notes
For research use only.
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