CXCR4 antagonist 5
CXCR4 antagonist 5 (compound 23) is a potent small molecule inhibitor of CXCR4 with an IC50 of 8.8 nM. It effectively blocks CXCL12-induced calcium mobilization and cell migration, and shows a favorable in vitro safety profile. This compound is a valuable research tool for studying CXCR4-related pathways in cancer, HIV, and inflammatory diseases.
Product Specifications
CAS Number
2304749-86-6
Field of Research
Cell Biology, Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Smiles
N (CC=1C=C (N=C (C) N1) N2CCN (C) CC2) (C) [C@@H]3C=4C (CCC3) =CC=CN4
Molecular Formula
C21H30N6
Molecular Weight
366.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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