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CXCR4 antagonist 5

CXCR4 antagonist 5 (compound 23) is a potent small molecule inhibitor of CXCR4 with an IC50 of 8.8 nM. It effectively blocks CXCL12-induced calcium mobilization and cell migration, and shows a favorable in vitro safety profile. This compound is a valuable research tool for studying CXCR4-related pathways in cancer, HIV, and inflammatory diseases.

Product Specifications

CAS Number

2304749-86-6

Field of Research

Cell Biology, Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Smiles

N (CC=1C=C (N=C (C) N1) N2CCN (C) CC2) (C) [C@@H]3C=4C (CCC3) =CC=CN4

Molecular Formula

C21H30N6

Molecular Weight

366.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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