OD36 hydrochloride
OD36 hydrochloride is a potent macrocyclic inhibitor of RIPK2 (IC50 = 5.3 nM) and ALK2 kinase (KD = 37 nM) . It effectively blocks the ATP-binding site, antagonizing mutant ALK2 signaling and osteogenic differentiation, making it a valuable tool for studying fibrodysplasia ossificans progressiva (FOP) in cellular and animal models.
Product Specifications
CAS Number
2387510-88-3
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.85% (May vary between batches)
Smiles
Cl.ClC=1C=C2OCCOCCN=C3C=CN4N=CC (C (C1) =C2) =C4N3
Molecular Formula
C16H16Cl2N4O2
Molecular Weight
367.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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