HDAC1-IN-5

HDAC1-IN-5 is a potent dual inhibitor of HDAC1 and HDAC6, inducing histone H3 and α-tubulin acetylation, caspase-3 activation, and apoptosis in cancer cells. It also binds DNA, causing chromatin damage, and has demonstrated significant antitumor efficacy in mouse xenograft models, supporting its use in oncology research.