HDAC1-IN-5
HDAC1-IN-5 is a potent dual inhibitor of HDAC1 and HDAC6, inducing histone H3 and α-tubulin acetylation, caspase-3 activation, and apoptosis in cancer cells. It also binds DNA, causing chromatin damage, and has demonstrated significant antitumor efficacy in mouse xenograft models, supporting its use in oncology research.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry, Signal Transduction
Molecular Formula
C20H21N3O2S
Molecular Weight
367.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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