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NFATc1-IN-1

NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclastogenesis (IC50 = 1.57 μM) that acts by blocking NFATc1 nuclear translocation. This mechanism supports its utility in foundational research on bone resorption disorders, including in vitro studies of osteoporosis and rheumatoid arthritis pathways.

Product Specifications

CAS Number

1912422-56-0

Product Name Alternative

RANK, RANKL

Field of Research

Signal Transduction

Purity

99.64% (May vary between batches)

Solubility

DMSO:112.5 mg/mL (299.91 mM)

Smiles

C (NC1=C (F) C=C (I) C=C1) (=O) C2=C (O) C=CC (F) =C2

Molecular Formula

C13H8F2INO2

Molecular Weight

375.11

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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