NFATc1-IN-1
NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclastogenesis (IC50 = 1.57 μM) that acts by blocking NFATc1 nuclear translocation. This mechanism supports its utility in foundational research on bone resorption disorders, including in vitro studies of osteoporosis and rheumatoid arthritis pathways.
Product Specifications
CAS Number
1912422-56-0
Product Name Alternative
RANK, RANKL
Field of Research
Signal Transduction
Purity
99.64% (May vary between batches)
Solubility
DMSO:112.5 mg/mL (299.91 mM)
Smiles
C (NC1=C (F) C=C (I) C=C1) (=O) C2=C (O) C=CC (F) =C2
Molecular Formula
C13H8F2INO2
Molecular Weight
375.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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