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Almorexant hydrochloride

Almorexant hydrochloride is an orally bioavailable dual orexin receptor antagonist that inhibits intracellular Ca2+ signaling. It has been used in sleep research to study orexin's role in arousal and has shown effects in reducing methamphetamine-induced excitatory responses in both in vitro and in vivo models.

Product Specifications

CAS Number

913358-93-7

Product Name Alternative

Inhibitor, inhibit, orexin, Orexin Receptor (OX Receptor), Orexin-RA-1 hydrochloride, OX Receptor, OX1, OX2, pancreatic cancer, Pancreatic ductal adenocarcinoma, PDAC, narcolepsy, hypocretin, Hypocretin Receptor, GPCR, HPAF-II cells, HCRT Receptor, A 573 hydrochloride, ACT 078573, ACT 078573 hydrochloride, ACT078573, ACT-078573, ACT078573 Hydrochloride, ACT-078573 hydrochloride, Almorexant, Almorexant HCl, Ca channels, Calcium Channel, Ca2+ channels, Caspase, Apoptosis, AsPC-1 cells, Cataplexy

Field of Research

Cell Biology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

99.85% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.64 mM) ; Ethanol:48 mg/mL (87.43 mM) ; DMSO:40 mg/mL (72.86 mM) ; H2O:< 0.1 mg/mL (insoluble)

Smiles

C (CC1=CC=C (C (F) (F) F) C=C1) [C@H]2C=3C (=CC (OC) =C (OC) C3) CCN2[C@@H] (C (NC) =O) C4=CC=CC=C4.Cl

Molecular Formula

C29H32ClF3N2O3

Molecular Weight

549.02

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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