ATG7-IN-3
ATG7-IN-3 (Compound 18) is a potent and selective ATG7 inhibitor with an IC50 of 48 nM, effectively blocking autophagy. It is a valuable research tool for investigating autophagy-dependent mechanisms in various cancer models, including gliomas and colorectal cancers, in both in vitro and in vivo studies.
Product Specifications
CAS Number
2226229-76-9
Field of Research
Cell Biology
Purity
99.74% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.77 mM) ; DMSO:80 mg/mL (212.53 mM)
Smiles
S (C) C1=NN (C=2C1=C (N) N=CN2) [C@@H]3O[C@H] (COS (N) (=O) =O) [C@@H] (O) C3
Molecular Formula
C11H16N6O5S2
Molecular Weight
376.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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