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Mt KARI-IN-2

Mt KARI-IN-2 (5b) is a potent and selective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Ki = 2.02 μM) with antitubercular activity (MIC = 0.78 μM against Mtb H37Rv) and low cytotoxicity. This compound is a valuable tool for investigating Mtb KARI's role in branched-chain amino acid biosynthesis and for in vitro antimycobacterial mechanism studies.

Product Specifications

CAS Number

2413974-52-2

Field of Research

Infectious Disease & Virology

Smiles

N (C (NC1=CC=C (OC) C=C1) =S) C=2SC (=NN2) C=3OC (N (=O) =O) =CC3

Molecular Formula

C14H11N5O4S2

Molecular Weight

377.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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