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TLR7/8 antagonist 2

TLR7/8 antagonist 2 is a potent, orally bioavailable dual antagonist of TLR7 and TLR8 with IC50 values of 4.9 nM and 0.6 nM, respectively. It serves as a valuable research tool for investigating autoimmune pathologies like lupus, where aberrant TLR7/8 signaling is implicated, in both cellular and animal model studies.

Product Specifications

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Molecular Formula

C22H26FN5

Molecular Weight

379.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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