TLR7/8 antagonist 2
TLR7/8 antagonist 2 is a potent, orally bioavailable dual antagonist of TLR7 and TLR8 with IC50 values of 4.9 nM and 0.6 nM, respectively. It serves as a valuable research tool for investigating autoimmune pathologies like lupus, where aberrant TLR7/8 signaling is implicated, in both cellular and animal model studies.
Product Specifications
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology
Molecular Formula
C22H26FN5
Molecular Weight
379.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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