PKC-IN-4
PKC-IN-4 (compound 7l) is a potent, orally bioavailable inhibitor of atypical PKC (IC50 = 0.52 μM) . It suppresses TNF-α-induced NF-κB activity in vitro and reduces VEGF/TNFα-mediated retinal vascular permeability, supporting research in oncology, inflammation, and diabetic retinopathy.
Product Specifications
CAS Number
2636771-29-2
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
C (N) C1CCN (C2=C3C (SC4=C3CCCC4) =NC (=N2) C=5C=CN=CC5) CC1
Molecular Formula
C21H25N5S
Molecular Weight
379.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
