TYK2-IN-11
TYK2-IN-11 (Compound 5B) is a highly potent and selective Tyk-2 inhibitor, exhibiting IC50 values of 0.016 nM against TYK2-JH2 and 0.31 nM against JAK1-JH2. This small molecule is a valuable research tool for investigating JAK/STAT signaling pathways in the context of autoimmune and inflammatory disease models, both in vitro and in vivo.
Product Specifications
CAS Number
2757009-40-6
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (C=1C (=CN=C (NC (C) =O) C1) C2=CC=CC=N2) C=3N=C (S (C) (=O) =O) C=CC3
Molecular Formula
C18H17N5O3S
Molecular Weight
383.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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