SBI-581
SBI-581 is a potent and selective oral TAO3 kinase inhibitor (IC50=42 nM) . It blocks invadopodia formation by promoting TKS5α accumulation on RAB11 vesicles and shows significant in vivo antitumor activity with reasonable pharmacokinetics in mouse models, supporting cancer metastasis research.
Product Specifications
Field of Research
Protein Biochemistry
Smiles
OC1 (C#CC2=CC=CC (NC/3=O) =C2C3=C\C4=CC5=C (C=CC=C5) N4) CCNCC1
Molecular Formula
C24H21N3O2
Molecular Weight
383.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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