SHP2-IN-9
SHP2-IN-9 is a potent and selective SHP2 inhibitor (IC50 = 1.174 μM) with an 85-fold preference over SHP1 and enhanced blood-brain barrier penetration. It blocks SHP2-dependent signaling, inhibiting cancer cell proliferation in vitro and suppressing tumor growth in models of cervical cancer and glioblastoma in vivo.
Product Specifications
Field of Research
Metabolism Research, Signal Transduction
Molecular Formula
C20H20FN3O2S
Molecular Weight
385.46
Storage Conditions
-20°C
Notes
For research use only.
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