BW 245C
Product Specifications
UNSPSC Description
BW 245C is a prostanoid DP-receptor (DP1) agonist, used to treat stroke.
Target Antigen
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/BW_245C.html
Purity
99.73
Solubility
DMSO : 50 mg/mL (ultrasonic;warming)
Smiles
O=C(O)CCCCCC[C@@H](C(N1)=O)N(CC[C@H](C2CCCCC2)O)C1=O
Molecular Weight
368.47
References & Citations
[1]Ahmad AS, et al. PGD<sub>2</sub> DP1 receptor stimulation following stroke ameliorates cerebral blood flow and outcomes. Neuroscience. 2014 Oct 24;279:260-8.|[2]Zhang S, et al. Prostaglandin D<sub>2</sub> receptor D-type prostanoid receptor 2 mediates eosinophil trafficking into the esophagus. Dis Esophagus. 2014 Aug;27(6):601-6.|[3]Ayabe S, et al. Prostaglandin D<sub>2</sub> inhibits collagen secretion from lung fibroblasts by activating the DP receptor. J Pharmacol Sci. 2013;121(4):312-7. Epub 2013 Mar 29.|[4]Kobayashi K, et al. Prostaglandin D<sub>2</sub>-DP signaling promotes endothelial barrier function via the cAMP/PKA/Tiam1/Rac1 pathway. Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):565-71.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101987/BW-245C-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101987/BW-245C-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
72814-32-5
Available Sizes
Curated Selection
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