PPARγ agonist 4
Compound 18b is a potent and selective PPARγ agonist that exhibits antitumor efficacy in combination with Imatinib, though it lacks inherent cytotoxicity against resistant or non-resistant cells. This profile makes it a useful research tool for studying combination therapies in oncology, particularly in models of Imatinib-sensitive cancers.
Product Specifications
CAS Number
2380227-06-3
Field of Research
Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Smiles
C (N1C=2C (N=C1CCC) =C (F) C=CC2) C3=CC=C (C=C3) C4=C (C (N) =O) C=CC=C4
Molecular Formula
C24H22FN3O
Molecular Weight
387.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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