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Dyrk1A-IN-5

Dyrk1A-IN-5 is a potent and selective DYRK1A inhibitor (IC50 = 6 nM) that reduces phosphorylation of SF3B1 (Thr434) and tau (Thr212) . This tool compound is used in Down syndrome research for investigating kinase function in cellular and biochemical assays.

Product Specifications

CAS Number

1685235-41-9

Field of Research

Cell Biology, Signal Transduction

Smiles

C (O) (=O) C1=C2C (=C3C (=N1) C=CC=C3) NC=4C2=CC=CC4I

Molecular Formula

C16H9IN2O2

Molecular Weight

388.16

Storage Conditions

-20°C

Notes

For research use only.

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