TEAD-IN-2
TEAD-IN-2 is a bifunctional small molecule that potently inhibits TEAD transcription factors and simultaneously recruits degradation machinery, leading to TEAD ubiquitination and proteasomal degradation. Its antiproliferative activity makes it a valuable chemical probe for studying Hippo pathway dysregulation in cancer research, both in cellular and animal models.
Product Specifications
CAS Number
2563849-97-6
Field of Research
Stem Cell & Developmental Biology
Smiles
FC (F) (F) C1=CC=C (C=C1) CN2CCC (CC2) C3ON=C (Br) C3
Molecular Formula
C16H18BrF3N2O
Molecular Weight
391.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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