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TEAD-IN-2

TEAD-IN-2 is a bifunctional small molecule that potently inhibits TEAD transcription factors and simultaneously recruits degradation machinery, leading to TEAD ubiquitination and proteasomal degradation. Its antiproliferative activity makes it a valuable chemical probe for studying Hippo pathway dysregulation in cancer research, both in cellular and animal models.

Product Specifications

CAS Number

2563849-97-6

Field of Research

Stem Cell & Developmental Biology

Smiles

FC (F) (F) C1=CC=C (C=C1) CN2CCC (CC2) C3ON=C (Br) C3

Molecular Formula

C16H18BrF3N2O

Molecular Weight

391.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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