RIPK1-IN-13
RIPK1-IN-13 (Compound 8) is a potent small molecule inhibitor of RIPK1 with an IC50 of 1139 nM, effectively blocking necroptosis. Its application extends to preclinical research in inflammatory disease models, where it is used to investigate RIPK1-driven pathology in both cellular and animal studies.
Product Specifications
CAS Number
1574547-67-3
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C1C2 (NC (=O) N1CC3=CC (Cl) =CC=C3) CCN (C (=O) C4=CC=CC=C4) CC2
Molecular Formula
C21H20ClN3O3
Molecular Weight
397.85
Storage Conditions
-20°C
Notes
For research use only.
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