AZD7254
AZD7254 is a potent and orally bioavailable Smoothened (SMO) antagonist with an EC50 of 1.0 nM against Sonic Hedgehog (Shh) signaling. This inhibitor is a valuable research tool for investigating the Hedgehog pathway in both cellular assays and in vivo models of related cancers and disorders.
Product Specifications
CAS Number
1126366-28-6
Field of Research
Stem Cell & Developmental Biology
Smiles
CC=1C (=CC (NC (=O) C2=CC=C (OCC3=CC=CC=N3) C=C2) =C (C) C1) C=4NC=CN4
Molecular Formula
C24H22N4O2
Molecular Weight
398.46
Storage Conditions
-20°C
Notes
For research use only.
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