SMO-IN-1
SMO-IN-1 (Compound 15) is a bioavailable, orally active inhibitor of the Smoothened (SMO) receptor with an EC50 of 89 nM against Sonic Hedgehog (Shh) signaling. This tool compound is used in both in vitro and in vivo studies to investigate the Hedgehog pathway's role in development and disease.
Product Specifications
CAS Number
1126365-66-9
Field of Research
Stem Cell & Developmental Biology
Smiles
N (C (=O) C1=CC=C (OCC2=CC=CC=N2) C=C1) C=3C=C (C=CC3C) C=4N=CN (C) C4
Molecular Formula
C24H22N4O2
Molecular Weight
398.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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