(R) -ONO-2952

(R) -ONO-2952 is the potent R-enantiomer of the selective, orally bioavailable TSPO antagonist ONO-2952, exhibiting high-affinity binding (Ki 0.330-9.30 nM) to both rat and human targets. This compound is a valuable research tool for investigating TSPO's role in neuroinflammation and anxiety in preclinical in vitro and in vivo models.