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ERRα antagonist-2

ERRα antagonist-2 (Compound 11) is an inverse agonist of estrogen-related receptor α with an IC50 of 0.80 μM. It inhibits the migration and invasion of ER-negative MDA-MB-231 breast cancer cells in vitro and has demonstrated efficacy in suppressing tumor growth in vivo.

Product Specifications

CAS Number

3032965-02-6

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

99.26% (May vary between batches)

Solubility

DMSO:200 mg/mL (499.49 mM)

Smiles

O=S (C (C=C1) =CC=C1[N+] ([O-]) =O) (NC2=C (OC3=CC=C (C=C3) OC) C=CC=C2) =O

Molecular Formula

C19H16N2O6S

Molecular Weight

400.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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