Calcium-sensing R/CaSR, Human (HEK293, His)

Calcium-sensing receptor (CaSR) is a G-protein-coupled receptor that is essential for maintaining calcium homeostasis. It senses changes in extracellular calcium concentration, regulates parathyroid hormone (PTH) production, and activates the phosphatidylinositol-calcium second messenger system. Calcium-sensing R/CaSR Protein, Human (HEK293, His) is the recombinant human-derived Calcium-sensing R/CaSR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Calcium-sensing R/CaSR Protein, Human (HEK293, His) is 582 a.a., with molecular weight of approximately 95-130 kDa.

YGPDQRAQKK GDIILGGLFP IHFGVAAKDQ DLKSRPESVE CIRYNFRGFR WLQAMIFAIE EINSSPALLP NLTLGYRIFD TCNTVSKALE ATLSFVAQNK IDSLNLDEFC NCSEHIPSTI AVVGATGSGV STAVANLLGL FYIPQVSYAS SSRLLSNKNQ FKSFLRTIPN DEHQATAMAD IIEYFRWNWV GTIAADDDYG RPGIEKFREE AEERDICIDF SELISQYSDE EEIQHVVEVI QNSTAKVIVV FSSGPDLEPL IKEIVRRNIT GKIWLASEAW ASSSLIAMPQ YFHVVGGTIG FALKAGQIPG FREFLKKVHP RKSVHNGFAK EFWEETFNCH LQEGAKGPLP VDTFLRGHEE SGDRFSNSST AFRPLCTGDE NISSVETPYI DYTHLRISYN VYLAVYSIAH ALQDIYTCLP GRGLFTNGSC ADIKKVEAWQ VLKHLRHLNF TNNMGEQVTF DECGDLVGNY SIINWHLSPE DGSIVFKEVG YYNVYAKKGE RLFINEEKIL WSGFSREVPF SNCSRDCLAG TRKGIIEGEP TCCFECVECP DGEYSDETDA SACNKCPDDF WSNENHTSCI AK