FLT3/D835Y-IN-1
FLT3/D835Y-IN-1 (13a) is a potent and selective oral inhibitor of FLT3 and its D835Y mutant, with IC50 values of 0.26 nM and 0.18 nM, respectively. It demonstrates anticancer activity in preclinical models, showing research utility for investigating acute myeloid leukemia (AML) in both cellular and animal studies.
Product Specifications
CAS Number
2648799-49-7
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C1\C (\C=2C (N1) =CC=CC2) =C/3\C (=N\OCC (=O) N4CCNCC4) \C=5C (N3) =CC=CC5
Molecular Formula
C22H21N5O3
Molecular Weight
403.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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