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FLT3/D835Y-IN-1

FLT3/D835Y-IN-1 (13a) is a potent and selective oral inhibitor of FLT3 and its D835Y mutant, with IC50 values of 0.26 nM and 0.18 nM, respectively. It demonstrates anticancer activity in preclinical models, showing research utility for investigating acute myeloid leukemia (AML) in both cellular and animal studies.

Product Specifications

CAS Number

2648799-49-7

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

O=C1\C (\C=2C (N1) =CC=CC2) =C/3\C (=N\OCC (=O) N4CCNCC4) \C=5C (N3) =CC=CC5

Molecular Formula

C22H21N5O3

Molecular Weight

403.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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