Ruxolitinib sulfate
Ruxolitinib sulfate is a selective JAK1/2 inhibitor with IC50 values of 3.3 nM and 2.8 nM, respectively, demonstrating over 130-fold selectivity against JAK3. It is widely used in research for myeloproliferative neoplasms, autoimmune diseases, and inflammation, with applications in both in vitro cellular assays and in vivo animal models.
Product Specifications
CAS Number
1092939-16-6
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
OS (O) (=O) =O.N#CC[C@@H] (C1CCCC1) n1cc (cn1) -c1ncnc2[nH]ccc12
Molecular Formula
C17H20N6O4S
Molecular Weight
404.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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