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Ledipasvir

Ledipasvir (GS-5885) is a small molecule NS5A inhibitor used in hepatitis C virus (HCV) research. It also acts as an inhibitor of the P-glycoprotein and Breast Cancer Resistance Protein (BCRP) transporters, making it a useful tool for in vitro and in vivo studies of drug efflux and pharmacokinetics.

Product Specifications

CAS Number

1256388-51-8

Product Name Alternative

SARSCoV, SARS coronavirus, SARS-CoV, Inhibitor, inhibit, Hepatitis C virus, HCV Protease, HCV, HCVProtease, Ledipasvir, GS 5885, GS5885, GS-5885, GT1a, GT1b

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

99.46% (May vary between batches)

Solubility

Ethanol:93 mg/mL (104.61 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (5.62 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:255 mg/mL (286.84 mM) ;2% DMSO+40% PEG300+5% Tween 80+53% Saline:1 mg/mL (1.12 mM)

Smiles

COC (=O) N[C@@H] (C (C) C) C (=O) N1CC2 (CC2) C[C@H]1c1ncc ([nH]1) -c1ccc2-c3ccc (cc3C (F) (F) c2c1) -c1ccc2nc ([nH]c2c1) [C@@H]1[C@H]2CC[C@H] (C2) N1C (=O) [C@@H] (NC (=O) OC) C (C) C

Molecular Formula

C49H54F2N8O6

Molecular Weight

889

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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