ABBV-318
ABBV-318 is a dual small molecule inhibitor of the voltage-gated sodium channels hNav1.7 and hNav1.8, exhibiting IC50 values of 2.8 μM and 3.8 μM, respectively. It serves as a research tool for investigating pain mechanisms and related disorders in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1802848-94-7
Product Name Alternative
Sodium Channel, SodiumChannel, Nav1.7 channel, Nav1.8 channel
Field of Research
Pharmacology & Drug Discovery
Purity
99.61% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.87 mM) ; DMSO:150 mg/mL (370.05 mM)
Smiles
F[C@@H]1CCN (C1) C (=O) c1ccc2cc (Oc3ccc (cn3) C (F) (F) F) ccc2n1
Molecular Formula
C20H15F4N3O2
Molecular Weight
405.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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